Here are some notes from the lecture:
Vocab: Character, Trait, Gene, Allele, Dominant Trait, Recessive Trait.
Mendel's First Law (Segregation) -- reveals the particulate nature of genes, while Mendel's second law (Independent Assortment), reveals that each character is passed on independently of the other. The results of the first and second laws "anticipate the role chromosomes play in genetics."
Monohybrid Cross results in a 3:1 ratio of phenotype inheritance. Dyhbrid cross results in a 9:3:3:1 ratio (if the genes for two characters assort independently).
Dominant and Recessive are not aspects of every gene. There's Incomplete Dominance (snapdragon example), as well as Co-dominance.
Some genes, such as blood type, have more than two alleles (blood has 3). Clover leaves. "Major Histocompatability" have hundreds.
Epistasis: Epistatic traits require more than one gene to be manifested (have gene for black fur, but need the dominant allele to express the phenotype).
Pleiotropy: One gene, many characters (Manx cat -- full tail, no tail, dead) -- also differences in red blood cells resulting in sickle cell anemia, but can also be completely normal, or even result in malaria resistance.
Phenotype can express differently, due to environmental factors, even if the responsible genes are transmitted in a purely Mendelian fashion (this affects most genes in a complicated way that we didn't really discuss at length).
One copy of each gene has to go into every gamete. This is one way we can ascertain evidence as to which alleles are independent of one another.
Sex linked chromosomes were discovered in fruit flies. Analogous situations in human beings are colorblindness and hemophilia.
Sex chromosomes do not determine gender, nor do they even determine sex characteristics in a consistent way across, between, or within species.
Barr body -- deactivated X chromosome, in an organism with multiple X chromosomes. Which X chromosome gets deactivated is random, and also randomly dispersed across all cells in the body.
Y chromosome carries very few genes. The rest are just "Junk DNA"
Bateson and Punnett, in their flower experiments, confirmed a suspicion that Mendel's second law was occasionally inaccurate. They discovered that genes located close together on the same chromosome often assort
dependently, not independently.
Additionally, genes almost universally cross over, so if genes assort interdependently, they are most likely on the same chromosome. But they don't have to be.
Here are the slides from this week